對於存在支氣管炎的马酸患者朋友們來說,想必對馬來酸氯苯那敏應該都不會感覺到陌生。氯苯與此同時馬來酸氯苯那敏還可以治療皮膚瘙癢,那敏神經性皮炎等疾病,马酸是氯苯一道非常不錯的止癢藥物。但是那敏畢竟是藥三分毒 ,長期使用馬來酸氯苯那敏的马酸話也會對患者朋友的身體造成一定的傷害,接下來就一起看一看馬來酸氯苯那敏的氯苯危害。
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馬來酸氯苯那敏片的主要成分為馬來酸氯苯那敏,其化學名為N,马酸N-二甲基 -γ-(4-氯苯基)-2-吡啶丙胺順丁烯二酸鹽。馬來酸氯苯那敏片主要用於治療於皮膚過敏症蕁麻疹、氯苯濕疹、那敏皮炎、马酸藥疹 、氯苯皮膚瘙癢症 、那敏神經性皮炎 、蟲咬症、日光性皮炎 、過敏性鼻炎,藥物及食物過敏等 。
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馬來酸氯苯那敏的作用機製是作為組織胺H1受體拮抗劑 ,馬來酸氯苯那敏能對抗過敏反應(組胺)所致的毛細血管擴張,降低毛細血管的通透性 ,緩解支氣管平滑肌收縮所致的喘息,馬來酸氯苯那敏抗組胺作用較持久,也具有明顯的中樞抑製作用,能增加麻醉藥 、鎮痛藥 、催眠藥和局麻藥的作用。
馬來酸氯苯那敏片除有較強的競爭性阻斷變態反應靶細胞上組胺H1受體的作用 ,通過對H1受體的拮抗起到抗過敏作用外,還具有抗M膽堿受體作用,故服藥後可出現口幹、便秘、痰液變稠、鼻黏膜幹燥等症狀。另外該藥還具有一定的抑製中樞的作用 ,因此可出現服藥後的困倦不良反應。馬來酸氯苯那敏片在服藥後可能會出現的副作用如嗜睡、口渴、多尿、咽喉痛、困倦、虛弱感、心悸 、皮膚瘀斑、出血傾向等。
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除此之外,服用馬來酸氯苯那敏片要注意以下事項:
1、與解熱鎮痛藥物配伍,可增強其鎮痛和緩解感冒症狀的作用。
2、與中樞鎮靜藥 、催眠藥、安定藥或乙醇並用,可增加對中樞神經的抑製作用 。
3、本品可增強抗抑鬱藥的作用 。
由此可見,馬來酸氯苯那敏片對身體的危害並不大,患者朋友可以放心使用。
(责任编辑:焦點)
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